HERBARIUM - HERBS AND SUPPLEMENTS FOR LYME DISEASE We have prepared a set of four FREE E-books which can answer the most frequent questions we are receiving and help you plan your therapy efficiently. Below you can see a brief description of the E-books: Practical Guide - Application of Herbal Therapies for Lyme Disease and Coinfections. The Guide contains a lot of practical knowledge about natural therapies used in Lyme disease. It will enable you to effectively plan therapy and facilitate progress monitoring. Therapy Planner. The Therapy Planner will enable you to plan your therapy systematically and effectively. Herbarium - Herbs and Supplements for Lyme Disease. The Herbarium contains a lot of information about herbs and supplements which you can use for particular symptoms. Lyme Disease Diet Guide. The Diet Guide can help you structure your diet in order to support your therapy. The E-books are intended equally for people who start their therapy as well as people who are already following some herbal protocols. The E-books are intended equally for people who start their therapy as well as people who are already following some herbal protocols. The E-books can be ordered here https://lymeherbs.eu/203-e-books We recommend you to download the pdf versions of the books. For your convenience this information is also available on our website. CONTENTS HERBS AND SUPPLEMENTS IN ALPHABETICAL ORDER. 3 SUGGESTED SELECTION OF HERBS. 20 Neuroborreliosis - Basic herbs for neurological symptoms. 20 Demyelination of neurons. 21 Bell's palsy. 21 Neurogenic pain. 21 Tremors. 22 Removal of bacterial neurotoxins. 22 Depression. 22 Chronic fatigue. 23 Brain fog, concentration and memory problems. 25 Joint problems. 25 Tremor, muscle numbness. 26 Cardiovascular problems. 26 Sleep problems. 27 Loss of libido. 27 Oedema, swelling and sluggish lymphatic system.. 27 References. 28 Copyright © Healthylife S.C., Chorzów 2022 All rights, including the right to reproduce the texts in whole or in part in any form, are reserved. Below you can find herbs and some supplements used for Lyme disease and tick-borne diseases presented in alphabetical order. We focused on those properties of herbs that are applicable to these diseases due to the nature of the guide. This will help you decide which herb or supplement to choose for your ailments. Remember that most herbs have a broad spectrum of action and their health properties go beyond what is found in the descriptions provided. Please note that general contraindications to the herbs listed below are pregnancy and lactation, taking immunosuppressive drugs and hypersensitivity to any of the ingredients. Additional contraindications will be indicated with individual herbs and supplements. NOTE: In the Therapy Planner, many herbs that you can use are listed next to a symptom. The descriptions below will help you quickly learn about the properties of a particular herb and any contraindications. However, you may still have a dilemma where to start. At the very end of this herbarium we prepared some suggestions of selection of herbs. Take a look at them. Then find these herbs in the alphabetical list of descriptions to learn more about them. Mark in the Therapy Planner which herbs you chose. The examples below are our suggestions. You can use them or make a different choice, more suited to your case. HERBS AND SUPPLEMENTS IN ALPHABETICAL ORDER Activated charcoal effectively absorbs toxins, which significantly accelerates their removal from the body. When using activated carbon, it is important to remember that it does not act selectively in the body, but binds everything without exception, including food substances and taken medications. Combining charcoal with solid medicines can contribute to absorption of the active substances of the medicine. Do not use activated charcoal in combination with medication. Adrenal Cortex is an extract of adrenal (bovine) cortex tissue. It supports normal adrenal function. It is used for the so-called adrenal fatigue, associated with a feeling of chronic fatigue. Adrenal Cortex also regulates cortisol levels and helps to support normal immune function. Alchornea cordifolia is a systemic herb, which means that when ingested, Alchornea's active ingredients concentrate in the bloodstream and are distributed throughout the body. They thus affect every cell and organ and counteract many bacteria and other microorganisms. In case of tick-borne diseases, Alchornea has found use against Babesia and Bartonella as well as against Candida, Staphylococcus aureus, Pseudomonas aeruginosa, E. coli and other resistant strains of Gram-positive and Gram-negative bacteria, among others. An additional known use of this herb is to protect red blood cells (erythrocytes). No contraindications were reported. Large doses can have a sedative effect on the central nervous system so it is better not to use large doses with antidepressants or sedative drugs. Alpha lipoic acid (ALA) has an important function in the metabolism of fats and amino acids in the human body. It is also a coenzyme of lipid oxidation pathways and a powerful antioxidant which protects the energy centres of somatic cells from the damaging effects of free radicals and metabolic stress. It promotes the maintenance of adequate amounts of glutathione and Q10 coenzyme. Furthermore, it supports the restoration of intracellular antioxidants such as vitamins C and E. Another important function of alpha lipoic acid is that it participates in the metabolism of ingested food, helping to convert it into energy. Alpha lipoic acid also supports the immune system as well as the treatment of autoimmune diseases. ALA acid is an important nutrient but it is also a mercury chelator. It is important to remember that alpha lipoic acid, due to its ability to pass through the blood-brain barrier, can carry mercury both ways (depending on the concentration gradient). If mercury levels in the blood were higher than in the brain, the mercury would enter the brain instead of being carried out of it. Therefore, ALA acid should not be used by people with chronic mercury poisoning or who have (current or past) amalgam fillings. Andrographis paniculata is the main herb in the Buhner Protocol that has antitreponemal effect. It readily crosses the blood-brain barrier and accumulates in the tissues of the central nervous system - in the brain, spinal cord, cerebrospinal fluid. Because of its broad systemic effect on the body, it both protects the body from damage due to infection and kills the spirochetes where they nested and at the same time provides an overall systemic immune boost. It protects the heart muscle. When using this herb, you must remember that it can cause allergic reactions in the form of rashes (in about 1% of people). You should start with a small dose and gradually increase it while observing the body's reaction. If such a reaction occurs, the herb should be discontinued. Angelica sinensis due to thecontent of coumarin dilates blood vessels, so it is excellent in improving blood circulation in internal organs and muscles. Angelica sinensis is also recommended in the treatment of neurosis, insomnia and respiratory diseases. It is also used to reduce Lyme neurotoxins (e.g. quinolinic acid). It can sometimes contribute to mild diarrhoea. Amantilla by Nutramedix is an extract made from the root of Valeriana officinalis, commonly known as valerian. Valerian is very effective in treating stress and anxiety as well as insomnia. It stimulates the production of GABA (gamma-aminobutyric acid) one of the amino acids produced in the brain, a substance described as a natural sedative for the body. Valerian extracts such as Amantilla stimulate the production of GABA in sufficient quantities to cause a calming effect. Therefore, Amantilla can cause sedation by increasing the amount of GABA available in synaptic gaps in the brain. Artemisia annua / Artemisinin both Artemisia annua (sweet wormwood) and its main active ingredient, artemisinin, show antimalarial activity, so they have found use in the treatment of Babesia infections and parasitic infections. Both Artemisia annua and artemisinin show systemic activity, i.e. they penetrate the intestinal barrier, concentrate in the bloodstream and are distributed throughout the body. Artemisia annua is a whole herb that includes both artemisinin and other synergistically acting compounds. This makes the spectrum of action of Artemisia annua much broader than that of a single, isolated substance. The use of a single, isolated substance in the form of artemisinin runs the risk of developing resistance, which is why it is necessary to take breaks during its intake. Ashwagandha (Indian ginseng, Lat. Withania somnifera) has very beneficial effects on the central nervous system and supports neurogenesis. Ashwagandha is also the most effective herb used in remodulating and lowering IL-10 cytokine levels and Th2 level responses which reduces many of the symptoms of Lyme disease and eliminates the infection from the body. We wrote about the effects of Borrelia bacteria on immune system remodulation in the “Practical Guide- Application of Herbal Therapies for Lyme Disease and Coinfections.” Ashwagandha is also known to be a mood stabiliser as well as has a positive effect on memory, concentration and sleep. Ashwagandha is a well-tolerated herb. It is worth introducing during therapy. The herb can cause excessive drowsiness. In rare cases, it can cause diarrhea or gastrointestinal disturbances. Do not use Ashwagandha in combination with sedative or anxiolytics. Astragalus membranceus is an immunostimulant herb. It increases levels of gamma interferon and interleukin 2. High levels of these reduce the likelihood of infection and if infection does occur, the effects of the disease will be much less, the development of symptoms weaker and the disease easier to treat. It should be taken by people living in Lyme disease endemic areas. It also increases CD4 titres and the CD4/CD8 ratio. The higher the level of CD4 white blood cells, the better the individual response to infection and treatment. Astragalus membranaceus is contraindicated in the late stage of Lyme disease because it stimulates the already increased TH1 reactions. This may worsen the symptoms of the disease. It is, however, indicated in pre, and early disseminated Lyme disease states. ATP 360® by Researched Nutritionals® is a comprehensive formula that supports mitochondrial function to increase the body's energy. Mitochondria are responsible for cellular energy production. Mitochondrial health can be affected by many health and environmental factors. ATP 360® is formulated to provide complete mitochondrial support by promoting normal mitochondrial growth and mitosis, supporting a healthy mitochondrial membrane and providing essential cofactors for optimal cellular energy production. ATP Fuel by Researched Nutritionals® supports mitochondrial function to increase body energy. It contains a patented phospholipid matrix that influences the proper functioning of mitochondrial membranes and supports the Krebs cycle and mitochondrial mitogenesis. It also contains antioxidants to protect the mitochondria from oxidative stress and nutrients such as NADH and CoQ10 to promote a healthy electron transport chain. BDNF Essentials® by Researched Nutritionals® stimulates brain-derived neurotrophic factor (BDNF), a protein secreted by neurons that belongs to the nerve growth factor family. Bentonite clay / Bentonite has properties that allow it to attract and absorb toxins and heavy metals without entering into any chemical reactions in the body. Bentonite creates an "electrical charge" in its hydrated state. When it comes into contact with water, it assumes a negative electrical charge. Toxins, bacteria, viruses, parasites and other impurities have a positive charge. When the clay enters the body, the toxins are attracted to it. What is extremely important is that bentonite is not absorbed into the body, so it is completely safe. It passes through the entire digestive system, absorbing toxins and heavy metals. At the same time, the minerals in the clay, such as calcium, magnesium, silicon, aluminium and potassium, are released and available for the body's metabolic processes. Finally, it is naturally excreted. You can find high-quality bentonite for internal use at https://www.zeolite-bentonite.com/. Barberry is a plant that contains an important active substance called berberine. Berberine exhibits a broad spectrum of antimicrobial activity. It acts against many bacteria such as Chlamydia, Escherichia coli, streptococci, staphylococci but also shows very strong activity against Candida. Berberine, various alkaloids and many other compounds contained in barberry work together in a highly synergistic manner. This increases the spectrum of action of the entire plant, prevents the development of resistance against microorganisms and additionally influences the body's immune mechanisms. The use of the whole plant is preferable to the use of a single isolated component in the form of berberine. Bidens pilosa is another herb with systemic effects which means that when ingested, the active ingredients of Bidens pilosa concentrate in the bloodstream and are distributed throughout the body. They thus affect every cell and organ and counteract many bacteria and other microorganisms. In tick-borne diseases, Bidens pilosa has found application against Babesia and Chlamydia. It has a protective effect on red blood cells. Bidens pilosa is effective against recurrent urinary tract infections and inflammations. It has a toning effect on the structural cells of the mucous membranes. It is also used in lung infections. It is also a reliable immune modulator. Boneset (Lat. Eupatorium perfoliatum) used as an auxiliary in occasional viral infections with intermittent fever (hot, then cold, etc.) but not as a primary therapeutic element. It is mainly used to reduce fever. Eupatorium perfoliatum can have a vomiting effect if drunk in too large quantities. If you feel nauseous when drinking tea made from this plant it is a sign that you are using too high dose. In this case, reduce the amount of tea you consume. Boswellia serrata has an anti-inflammatory effect in case of arthritis and osteoarthritis and an analgesic effect in case of back pain. It has immunomodulatory, anxiolytic and antineurotic properties. Boswellia also has a beneficial effect on the intestines. Bromelain is a proteolytic enzyme found in pineapple the main function of which is to destroy peptide bonds. Bromelain helps to inhibit the production of compounds that cause pain and inflammation, while also promoting the stimulation of the production of the so-called prostaglandins (hormone-like substances) which have anti-inflammatory properties. Thanks to its strong anti-inflammatory and analgesic properties, bromelain is a good supplement for people suffering from acute or chronic joint pain. Bromelain also reduces swelling and pain resulting from injuries or muscle damage. It speeds up the healing of wounds. Burbur by Nutramedix is an extract made from the leaves of Desmodium molliculum. The herb is traditionally used to cleanse the body. It is very effective in supporting detoxification of the liver, kidneys, lymphatic system and cellular matrix. It protects the liver from external toxins such as certain chemicals and toxic moulds. It also alleviates the Herx response, the unwanted effects of pathogen die-offs. Burbur-Pinella by Nutramedix is a combination of two extracts: Burbur - derived from Desmodium molliculum and Pinella derived from Pimpinella anisum. Burbur-Pinella supports detoxification of the brain and central nervous system, cleanses the body of toxins and biotoxins, detoxifies the liver, kidneys, lymphatic system and intercellular spaces, purifies the blood. It eliminates toxins from the brain, spine and peripheral nervous system. Burbur-Pinella is also effective in reducing Herx reactions. Cat's Claw (Lat. Uncaria tomentosa) is the primary herb in the Buhner protocol recommended for immune system regulation. This herb modulates the action of the immune system, increasing its strength when necessary and, if necessary, lowering excessive reactions. One of the most beneficial aspects of treating Lyme disease with Cat's Claw is that it contributes to the growth of CD57+ cells which play an important role in the proper functioning of the immune system. When Lyme spirochetes are present in the body, they specifically inhibit the production of this subset of immune system cells. A low CD57 titer is a reliable marker in chronic Lyme disease, especially when antibiotic therapy has no effect. This ability to increase the CD57 cell count in Lyme disease patients is one of the reasons for the good results in the treatment of chronic or late Lyme disease. The use of Cat's Claw helps to maintain high levels of CD57, which in turn helps to inhibit the progression of the disease. In addition, it has a specific anti-inflammatory effect in the treatment of joint and muscle pain in Lyme disease, reduces swelling and also has a positive effect on the nervous system. Cat's claw must not be taken by people taking blood thinners. People who are scheduled for surgery must stop taking the herb 10 days before any planned surgery. Cat's Claw should not be taken during treatment with drugs that inhibit gastric acid secretion because these can also inhibit the conversion of the herb to its active form in the stomach. CBD oil extracted from hemp seed is non-psychoactive and can be used as a versatile therapeutic agent without fear of altering consciousness. It has a broad spectrum of action. However, focusing on its functions in the nervous system, it is important to note its neuroactive and neuroprotective properties. CBD oil is used in neurodegenerative and psychiatric disorders. It regenerates nerve cells, has a protective effect on the nervous system, counteracts and prevents neurodegeneration and has a relaxing effect. An important effect of CBD oil is its analgesic properties. Cannabidiol, the key ingredient in hemp, soothes and eliminates pain throughout the body. Hemp oil is contraindicated for coronary artery disease and reduced blood clotting. Celery seeds have large amounts of the pain-relieving and deacidifying apigenin. It helps to reduce the acids that cause joint capsulitis and other inflammatory conditions. The benefits of adding celery seeds to your diet or drinking an infusion of freshly crushed celery seeds are that they reduce the amount of metabolic acids in the body that cause inflammation and arthritis symptoms. In addition, celery seeds improve urine quality and quantity and are a useful diuretic in the treatment of acid urinary tract inflammation. Chinsese senega has found use in Lyme disease due to its positive effects on nervous system function. The herb is used for cognitive disorders, memory loss and depression. One of the most important functions of this herb is its effect on stimulating the nerve growth factor (NGF) which is essential for neuron proliferation and survival and stimulating the process of myelination (production of myelin sheaths - responsible for protection and nutrition - around nerve cell axons). Chinese Senega has strong anti-inflammatory effects. It is also used for inflammation of the respiratory tract and for pneumonia and asthma. Chinese skullcap (Baikal skullcap, Lat. Scutellaria baicalensis) acts as a modulator of the cytokine cascade, i.e. a regulator of inflammatory processes taking place in the nervous system. The spectrum of action of this herb is wide. In addition to its positive effects on the nervous system, Baikal skullcap has strong antiviral and antibacterial effects. It reduces the replication of pathogens, suppresses the expression of viral genes, interferes with the penetration of viruses, affects the functions of the immune system and has many other health-promoting properties. Chinese skullcap is also a very good synergist. Synergy means that the combination of two (or more) factors gives better results than the sum of the parts, i.e. the effect is intensified. So Chinese skullcap goes very well in combination with herbs but when you want to combine it with medicines, be sure to consult your doctor. Chinese skullcap can affect insulin and blood sugar levels, so people with type 1 diabetes should be cautious. The plant can interact with medications that lower blood pressure. Chlorella has unique properties that neutralise toxic substances accumulated in the body as a result of environmental pollution or the consumption of contaminated products. It cleanses the body of heavy metals and some pesticides. Chlorella also absorbs toxins from the intestines, it helps to get rid of chronic constipation and neutralises intestinal gases. Chlorella is safe for health and well tolerated, but in individual cases it can cause side effects such as diarrhoea, flatulence, abdominal cramps or green stools. Chlorophyll is a powerful antioxidant which protects our body from free radicals and slows down the ageing process. It has a positive effect on stimulating blood production. It supports the treatment and prevention of cardiovascular diseases. Chlorophyll supplied to the body increases the production of oxygen. Thanks to this, the cells are oxygenated and the processes of detoxification occurring in the body run more efficiently. Chlorophyll strengthens immunity, supports the fight against viruses and bacteria. It rebuilds damaged bacterial flora in the intestines, thanks to which it improves digestion and prevents flatulence and stomach ailments. The magnesium contained in it has a positive effect on the nervous system and helps to reduce stress. Cistus is a well-known supportive herb for Lyme disease. It has antibacterial and antiviral properties. The Cistus Creticus variety of cistus inhibits the growth of Lyme spirochetes but it neither kill them nor remove them from the body. The compounds in it glue viruses and bacteria together, thus preventing them from binding to the cell membrane. Drinking Cistus during therapy is a very good support. In addition, the polyphenols contained in Cistus are powerful antioxidants. Cleavers (Lat. Galium aparine) contains a number of health promoting substances. This plant has the ability to reduce swelling and restore optimal water retention in the body. The Cleavers therapy cleanses the lymphatic system and strengthens the liver, spleen and pancreas. Cleavers also cleanses the blood and the lymphatic system, but above all improves blood circulation. It has a diuretic effect and therefore supports the treatment of inflammatory conditions of the urinary system. In addition, it has anti-inflammatory properties, strengthens the walls of blood vessels, acts as a diastolic, diaphoretic, antiseptic and stimulates metabolism. Coenzyme Q10 (CoQ10) is a natural substance produced by the body. It is essential for the functioning of every cell in the body. It is also an essential component of the mitochondrion. CoQ10 participates in the production of ATP. ATP is the main source of energy in the cell and is essential for the proper functioning of a number of biological processes. It is also responsible for supplying cells with energy needed in the processes of regeneration and growth. Coenzyme Q10 supplementation is crucial for people with chronic fatigue. Coenzyme Q10 is also a very strong antioxidant, so it protects against the harmful effects of free radicals. CoQ10 strengthens the immune system. In states of impaired immunity it is important to maintain optimal levels of coenzyme Q10 so that cells involved in the functioning of the immune system can be provided with adequate amounts of energy. People suffering from diabetes or heart disease should consult a doctor before supplementing with coenzyme Q10. Cordyceps is a medicinal fungi. It is a powerful adaptogen. It protects mitochondria, supports cellular respiration processes and stimulates ATP production. It has an immunomodulating effect, i.e. if the immunological activity is too high, the fungi lowers it, and if it is too low, it raises it. On the one hand, it has an antibacterial effect and at the same time it lowers the concentration of inflammatory cytokines. It strengthens the heart muscle and lowers blood pressure. It helps with a reduced sex drive and problems with memory and concentration and the so-called brain fog. Cryptolepis sanguinolenta is another herb of systemic effect which means that when ingested, the active ingredients of Cryptolepis sanguinolenta concentrate in the bloodstream and are distributed throughout the body. In this way, they affect every cell and organ and counteract many bacteria and other microorganisms. In tick-borne diseases, Cryptolepis sanguinolenta is used against Borrelia, Babesia, Yersinia and other resistant bacterial infections such as staphylococcus. D-ribose acts as a fuel for energy production in the mitochondria. It is recommended in case of mitochondrial function impairment. Therefore, it is suitable for people who suffer from chronic fatigue. D-ribose should not be used by people with metabolic syndrome and diabetes who have an elevated level of glycation. Devil's claw (grapple plant, wood spider, Lat. Harpagophytum procumbens) shows quite strong anti-inflammatory and anti-rheumatic effects as well as analgesic activity. It is therefore used for joint and muscle pains and inflammations. Echinacea augustifolia (narrow-leaved purple coneflower) not to be confused with the more popular Echinacea purpurea. Echinacea augustifolia is used to protect and repair collagen tissue. It stimulates collagen production. A tincture of this plant diluted with a small amount of water can be used to wash wounds and accelerate healing. E. augustifolia is a strong analgesic. It shows antibacterial and antiviral effects. It is a perfect solution for throat diseases and tonsillitis. In this case, ½ teaspoon of Echinacea augustifolia tincture, without dilution, should be kept in the mouth until the saliva is well stimulated, then swallowed slowly by spreading over the diseased areas of the throat. Repeat every hour. Remember that this is a herb that stimulates the immune system. Use cautiously if you have a co-existing autoimmune disease. EGCG is the most active catechin found in green tea which determines its health-promoting properties. This compound is an extremely powerful antioxidant, neutralising free radicals. EGCG has stronger antioxidant properties than vitamins C and E. EGCG also has neuroprotective effects. This substance has a significant effect on the body's immunity as it increases the number of the so-called regulatory T lymphocytes (Treg) - cells belonging to the immune system, which are mainly responsible for inhibiting the immune response, including autoimmunity. EGCG supports the metabolism, being an element in the prevention of atherosclerosis. Furthermore, EGCG lowers blood pressure and thus reduces the risk of stroke or cardiovascular episodes. EGCG also helps to lower glucose levels. EGCG should not be used by people with a diagnosed hypersensitivity to caffeine. Energy Multi-Plex is another highly effective product from Researched Nutritionals®. Energy Multi-Plex provides comprehensive adrenal support with a proprietary blend of 14 researched nutrients. The vegan formula supports energy production and adrenal function without the negative effects that can accompany glandular-based supplements which can cause over-stimulation of the adrenals. While glandular supplements attempt to do the work of the adrenal glands, Energy Multi-Plex™ provides nutrients that directly and naturally support the adrenal glands for optimal energy. Epsom salt baths are an excellent support in cleansing the body. These are the so-called alkaline baths. They have deacidifying and detoxifying properties. The sulphates contained in Epsom salt help rid the body of toxins and heavy metals. Folic acid, or vitamin B9 in its active form, participates indirectly in the production and maintenance of standard levels of many neurotransmitters. Neurotransmitters such as serotonin, dopamine and acetylcholine are responsible for important functions such as memory, mental clarity, alertness and moods. A reduced intake of folic acid can therefore lead to depression and cognitive decline. Folic acid is also involved in the synthesis of nucleic acids, from which DNA is formed. Thus, it regulates the growth and function of all cells. Together with other B vitamins, folic acid also influences homocysteine levels. Folic acid is also necessary for the proper functioning of the haematopoietic system and its deficiency can lead to anaemia. GABA -L-theanine is a dietary supplement containing L-theanine. L-theanine is a derivative of green tea which has a relaxing effect on the body and also has a positive effect on the reuptake of glutamic acid in the brain. L-theanine increases the levels of serotonin, dopamine and GABA - neurotransmitters which are responsible for good mood and emotions, among other things. This amino acid also increases the activity of alpha brain waves, which are present during a state of deep mental relaxation and during sleep in the REM phase. As this substance deepens and prolongs this very phase of sleep, it improves its quality. At the same time, L-theanine facilitates falling asleep by increasing the effectiveness of the GABA system which is an anti-anxiety neurotransmitter. It allows the mind to slow down thought processes and prepare for sleep. L-theanine also has a neuroprotective effect. People taking blood pressure-lowering drugs and drugs that stimulate the nervous system should consult their doctor about taking L-theanine. Ginkgo biloba (Maidenhair tree) helps in correct functioning of blood vessels. It influences the proper functioning of the nervous system, protects the nervous tissue preventing degradation of myelin sheaths and neurolemma. Ginkgo biloba is used in order to reduce symptoms connected with memory disorders, cognitive disorders, difficulty in finding words and brain fog. Ginkgo biloba also protects against the damaging effects of free radicals and exhibits antioxidant effects. By improving blood supply to the brain and skeletal muscles, it increases physical and mental efficiency. People suffering from cardiovascular diseases should consult a doctor before taking ginkgo biloba. Glucosamine shows anti-inflammatory properties and stimulates synthesis of collagen. It participates in synthesis of proteoglycans (building substances of articular cartilage), which allows strengthening and even regeneration of pathologically changed joints. It protects tissues against fibrosis, which supports the treatment of osteoarthritis. It also contributes to the reduction of certain enzymes involved in the degradation of joint cartilage. It is recommended to combine glucosamine with chondroitin. Glutathione is a powerful antioxidant, a key substance that protects cells from the toxic effects of free radicals formed as toxic metabolites during natural intracellular metabolism and those entering with toxins from outside. If the level of glutathione in the body decreases, the body's overall ability to detoxify itself significantly decreases. Glutathione has the ability to dissolve toxins, which can then be excreted from the body. It cleanses the body of heavy metals, herbicides, pesticides, toxic components of tobacco smoke and other harmful substances. Glutathione also has a positive effect on proper liver function. Another important function of glutathione is its influence on the work of the immune system. It increases the production of leukocytes and conditions their effective action. The immune system functions efficiently only in a body in which the level of glutathione is sufficiently high. Only then can the body effectively detect and destroy bacteria, viruses, foreign antigens and cancer cells and prevent their multiplication. The production of glutathione is supported by NAC, so it is worth using these two products together. Glycine is the simplest protein amino acid. Glycine has a significant effect on the functioning of the nervous system. It contributes to improved brain function and enhanced cognitive functions such as memory and concentration. It also improves the quality of sleep and shortens the time to fall asleep, making it a valuable support for people with insomnia. This valuable amino acid also supports the work of the immune system. It participates in the production of hormones. It also contributes to detoxification of the body, cleansing it of harmful substances. Glycine is necessary for the synthesis of glutathione, a powerful antioxidant. Goldenseal (Lat. Hydrastis canadensis) is a plant that is a rich source of berberine. It is considered to be one of the best natural antibiotics. It has a healing effect on all mucous membranes in the body. Thanks to the presence of berberine, the herb is useful against Chlamydia pneumoniae bacteria. It effectively eliminates Candida fungus colonies and numerous bacteria without destroying beneficial flora. Berberine, which is the main component of this plant, even has a beneficial effect on intestinal microflora, restoring its proper balance. The herb is also used in upper respiratory infections due to its expectorant and cough suppressant effects. Goldenseal should not be taken by people with high blood pressure, hypoglycaemia or enzyme insufficiency. It should not be administered to people with an autoimmune disease such as multiple sclerosis or lupus. Gotu kola (Lat. Centella asiatica) helps to maintain the elasticity of vein walls and capillaries and supports the circulatory system. It also supports healthy blood circulation in the brain and has a positive effect on cognitive functions such as memory and concentration. Buhner recommends the use of Gotu kola in its extended protocol for Lyme disease to reduce neurological symptoms associated with memory impairment, cognitive impairment, difficulties in finding words and brain fog. Gotu kola does not affect blood pressure, but improves blood circulation and microcirculation in capillaries. The beneficial effect of Centella asiatica active compounds on the synthesis of collagen, elastin and the structure of blood vessels has been proven. Moreover, Gotu kola improves mood, reduces symptoms of stress and lowers sensitivity to stress. It has sedative, antidepressant, anticonvulsant and analgesic effects. Gou teng (Lat. Uncaria rhynchophylla) is a herb that supports nervous structures. It also has anti-inflammatory effects on the nervous system and anti-epileptic effects. It also has antibacterial and relaxing effect on smooth muscles as well as systemic tonic effects. Gou teng lowers blood pressure, so people with low blood pressure should swap this herb for another if their blood pressure drops. Greater celandine (Lat. Chelidonium majus) is a herb mainly affecting the central nervous system and liver. Chelidonium's active constituent, chelidonin, has the same effect on the central nervous system as morphine but weaker (it does not cause euphoria). The herb is also used in states of excessive emotional agitation. It also shows neuroprotective effects. Greater celandine increases bile flow, therefore obstruction of bile ducts and coexisting or past liver diseases are contraindications. Greater celandineshould not be used with other drugs, especially paracetamol. The herb should be used for no more than one month. If you wish to repeat the treatment, take a 1-2 week break first before using Greater celandineagain. Hawthorn (Lat. Crataegus oxyacantha) is effective in connection with almost all symptoms of heart disease: atherosclerosis, cardiac arrhythmia, congestive heart failure, hypertension and peripheral vascular disease. The plant lowers blood pressure, dilates blood vessels throughout the body, lowers blood cholesterol levels, regulates heart rate, slows and normalizes heartbeat. People with low blood pressure should avoid Hawthorn. Houttuynia cordata is a herb used for Lyme, Bartonella and Mycoplasma infections. It is also a herb with strong antiviral properties. It inhibits viral replication and prevents viral infections. Houttuynia has immunomodulatory and anti-inflammatory properties. Houttuynia has a specific fishy smell and aftertaste. Isatis is a herb used for Bartonella and Mycoplasma infections. It is also a herb with strong antiviral properties. It shows anti-inflammatory effects and is an immunostimulant. The herb should not be taken for more than 3 weeks in a row. After this time, take a break before returning to its use again. High doses or prolonged intake can stress the kidneys. It shows synergy with antibiotics and antiviral vaccines. It may increase the activity of these preparations. Japanese knotweed (Lat. Polygonum cuspidatum) is the primary herb included in the Buhner Protocol. Its role in the treatment of Lyme disease is significant. Japanese knotweed is a herb that exhibits antimicrobial activity, including activity against Lyme spirochetes as well as antiviral activity. It protects the integrity of the vascular endothelium which prevents the penetration of Borrelia bacteria and other co-infections, thus protecting against damage caused by them. It stimulates microcirculation, especially in the joints, heart, eyeballs, brain and skin and is therefore important in transporting active ingredients to areas affected by pathogenic microorganisms. The active ingredients of Japanese knotweed pass through the blood-brain barrier and affect the central nervous system where they have anti-spirochete and anti-inflammatory effects. Japanese Knotweed contributes to the reduction of inflammation in tissues and therefore reduces the impact of Borrelia bacteria in both joints and skin. It protects and improves heart function and reduces inflammation in tissues and is helpful for cardiac symptoms in Lyme disease such as palpitations, chest pain, shortness of breath and dizziness. Importantly, it lowers the body's autoimmune response to Lyme disease. It helps to lower the strength of the Herxheimer reaction. This herb also reduces the production of reactive oxygen species in the brain and central nervous system. Japanese knotweed should not be used together with blood thinners. The use of this herb should be discontinued ten days before a planned surgical procedure. Korean ginseng (Lat. Panax ginseng) increases vitality and improves blood flow. It also contributes to the reduction of mental fatigue and stress levels. It contributes to strengthening immune system functions as it activates lymphocytes (immune system cells). Korean ginseng also contributes to the improvement of sexual function in men. It contributes to lowering blood glucose levels and improving lipid metabolism. Korean ginseng has an overall stimulating and strengthening effect on motor and secretory centres. Unlike Siberian ginseng, Korean ginseng has a lowering effect on blood pressure. People with a tendency to low blood pressure should exercise caution when using this variety of ginseng. Kudzu (Lat. Pueraria lobata) has a number of health-promoting properties. The components contained in the plant show anti-inflammatory and antioxidant effects. Puerarin is considered to be a particularly valuable ingredient, which exhibits anti-arrhythmic, blood circulation promoting and anti-diabetic effects. Kudzu has become popular as a support for addiction treatment, but it also has positive effects on the nervous system. It shows anti-inflammatory effects within the nervous system. It is useful for the symptom of feeling “pressure” in the brain or neurogenic pain. L-arginine is an amino acid from the endogenous group, used in many physiological processes of human metabolism. Its main function is the production of nitric oxide (NO), whose main action is to facilitate the transport of nutrients to muscle tissue. L-arginine influences the dilation of blood vessels. It also participates in such processes as the synthesis of growth hormone and detoxification of harmful metabolic products. It may help with erectile dysfunction and improve sexual function. It helps relax blood vessels so that more oxygen-rich blood can circulate in the arteries. Unobstructed blood flow to the penile arteries is essential for the proper functioning of this organ. L-arginine should not be used by people suffering from asthma, problems with bile duct patency, high blood pressure, digestive disorders, hypersensitivity and impaired kidney function and liver failure. Arginine should not be used by people suffering from schizophrenia. Long-term use of the supplement (without a break period) may lead to the production of excessive amounts of nitric oxide, resulting in increased blood pressure and decreased heart muscle performance. Gastrointestinal problems can also occur. L-carnitine, and preferably its acetylated form, acetyl-l-carnitine, is essential for the correct functioning of the nervous and muscular systems. Acetyl-L-carnitine stimulates cells to produce the neurotransmitter dopamine and also intensifies its actions. Dopamine is a neurotransmitter responsible for thought processes, mood, motor coordination and resistance to stress. It also maintains the normal activity of the nerve growth factor NGF, responsible for the health and proper functioning of neurons. A very important function of acetyl-L-carnitine is to help transport fatty acids to the mitochondria, our body's energy centres. Another important aspect of its action is its neuroprotective properties. Acetyl-L-carnitine plays a significant role in protecting nerve cells, including brain cells, from many adverse factors. This is because it prevents the ageing and degradation of nerve cells. In addition, acetyl-L-carnitine provides the body with the so-called acetyl groups for the production of acetylcholine - a very important neurotransmitter in the nervous system and in nerve and muscle connections. Acetyl-L-carnitine has strong antioxidant properties and therefore protects against free radicals. Acetyl-L-carnitine should not be taken by people who suffer from epilepsy. Licorice (Liquorice) is a herb used for Babesia, Chlamydia, Ehrlichia and Yersinia. It is also a herb with strong antiviral properties and a powerful synergist. Synergistic herbs are those that facilitate and enhance the action of other plants and pharmaceuticals. Licorice should therefore be used in combination with other herbs. The reported side effects relate to the use of this herb in large quantities and as a sole preparation (rather than in a synergistic combination). In this case, do not use Licorice for more than 4-6 weeks. Used alone or in large doses, it can cause, among other things, numbness, oedema, limb weakness, dizziness, headache or hypertension especially in the case of older people. Licorice is contraindicated when suffering from hypertension, hypokalaemia, hypernatraemia and in case of low testosterone levels. Lion's mane (Mountain-priest mushroom, Lat. Hericium erinaceus) is a fungus with unique properties that protects the nervous system and supports its development and regeneration. It is known for its neuroprotective and neuroregenerative properties. It stimulates the nerve growth factor NGF essential for proliferation and survival of neurons and stimulates the process of myelinisation (production of myelin sheaths responsible for protection and nutrition around nerve cell axons). Buhner recommends Lion's mane in his extended protocol for Lyme disease to reduce neurological symptoms and restore neuronal structures. In addition, taking Lion's mane is indicated for all gastrointestinal complaints. It shows a soothing effect in stomach ulcers and in precancerous conditions of the digestive system. Lutein, together with zeaxanthin stored in the lens and retina, it counteracts harmful UV radiation. It filters blue light and can protect the macula lutea from free radical damage. A healthy macula enables proper central vision. Lutein has a positive effect on visual acuity and prevents dangerous eye diseases. Lutein accumulates not only in the eye tissue, but also in other tissues, such as skin tissue. Lutein makes the skin more elastic and improves the hydration of its tissues. It also normalises the sebaceous glands and contributes to an increase in the lipid layer of the epidermis. Lutein is also an important nutrient that has a positive effect on the cardiovascular system. Maca (Lat. Lepidium meyenii) is an excellent adaptogen. This herb improves adrenal and thyroid functions, it has a positive effect on hormonal balance. Maca stimulates energetically and strengthens physical endurance of the body. Moreover, it improves sexual functions and sex drive in men and women. It stimulates development of connections between neurons, influencing memory and ability to assimilate knowledge. Melatonin, otherwise known as the "sleep hormone" is produced mainly in the pineal gland. The level of its concentration in the body varies depending on the time of day. Melatonin synchronizes the work of the biological clock with the diurnal cycle - it regulates the daily cycle of sleep and wakefulness. The majority of sleep disorders occur as a result of incompatibility between the body's diurnal rhythm and the one imposed by the lifestyle. That is why melatonin is recommended for people with insomnia problems. Milk thistle (Lat. Silybum marianum) has apositive effect on liver function. It protects the liver against toxic and pathogenic factors. It stimulates liver cleansing and regeneration of a damaged liver. It shows antioxidant and immunostimulating properties. Motherwort (Lat. Leonurus cardiaca) is recommended for migraines and depression because of its sedative properties. It acts on the central and vegetative nervous system. It also regulates the work of the heart during stress. MSM or organic sulphur, is essential for the production of many enzymes, collagen, keratin, connective tissue and antibodies. MSM alleviates symptoms associated with various osteoarticular system disorders. Organic sulphur, by stimulating collagen production, accelerates muscle regeneration and strengthens joints. Moreover, it perfectly nourishes bones and joints, builds cartilage and improves the condition of joint fluid. It is responsible for reduction of pain, oedema and stiffness of joints but also reduces inflammation within them. NAC (N-acetyl-L-cysteine) is a specific form of the sulphur amino acid cysteine which is commonly found in our bodies and in food proteins. Cysteine is included in human structural proteins, including skeletal muscle. Cysteine is a precursor of glutathione - one of the most important antioxidants, the most powerful substance protecting our organism against free oxygen radicals, many toxins and pathogens. Glutathione supports the removal of toxins from our organism, regenerates damaged proteins and supports the reconstruction of other antioxidants. NAC additionally has mucolytic effects, i.e. it liquefies and reduces the viscosity of mucus, thanks to which it has a beneficial effect in respiratory disorders as it facilitates the removal of excess secretions from the respiratory tract. N-acetyl-cysteine also has a beneficial effect on the liver. It helps restore liver cells, improves liver function, prevents liver damage and reduces damage caused by drugs, oral anabolic steroids or alcohol. Moreover, it reduces the toxic properties of heavy metals, accelerating their elimination from the body. NAC reduces inflammation in tissues and boosts immunity by reducing oxidative stress, influencing the production of post-inflammatory cytokines and the immune response as well as having an antioxidant effect. N-acetyl-cysteine has also found application in autoimmune diseases. Chronic inflammation and the resulting oxidative stress underlie autoimmune diseases such as Hashimoto's disease, multiple sclerosis, RA, and inflammatory bowel diseases. The use of NAC can help reduce inflammation and slow down autoimmune tissue destruction. Caution in supplementation should be exercised by people with asthma, coagulation disorders, excessive bleeding, peptic ulcer disease, respiratory insufficiency, and some methylation disorders. NADH, or nicotinamide adenine dinucleotide, also known as coenzyme Q1, is an essential molecule for generating energy in the body, regulating key processes in the body, and for proper mitochondrial function. NADH determines processes of energy acquisition in cells. It is part of the electron transport chain that produces energy. Nettle (Lat. Urtica dioica) has diuretic properties. It can be used as a supportive agent in case of oedemas because it helps to remove retained liquids from the body. Nettle also has anti-inflammatory effects and is helpful in arthritis. It inhibits elastase, a natural substance in the human body which leads to the breakdown of elastin, cartilage, collagen and fibronectin. Nettle is not recommended for women with diseases of reproductive organs such as cancer, myomata, cysts or bleeding. It is also not suitable for chronic kidney disease, surgery or diabetes. NT Factor Energy is a patented formula by Researched Nutritionals® that supports mitochondrial function to increase body energy. The ingredients in NT Factor Energy affect the mitochondrial membranes and provide the mitochondria with key nutrients and support ATP production. Olive leaf has strong antifungal properties, including against Candida, which is why it is used in candidiasis. It is also antibacterial, antiparasitic and antiviral. It helps fight resistant bacteria (e.g. Mycoplasma) and fungi because it reaches the cell membrane of the microorganism and dissolves it, thus opening the way for the destruction of the pathogen. Olive leaf improves the functioning of the immune system and has anti-inflammatory effects. It has 400% more antioxidants than vitamin C and twice as many as green tea. Olive leaf stimulates the immune system and helps stabilize blood sugar levels (increased blood sugar levels increase the growth of Candida and the development of candidiasis). It also makes the arteries more flexible, which improves blood flow and reduces blood pressure. Parsley Detox by Nutramedix is an extract of parsley leaves (Lat. Petroselinum crispum). It cleanses the body of toxins and biotoxins, detoxifies the liver, kidneys, lymphatic system and intercellular spaces, it purifies the blood. Parsley Detox is also effective in reducing Herx reactions. In addition, it supplements deficiencies of calcium, iron, thiamine, riboflavin, carotenes, vitamin A and vitamin C. PEA by Nutrined is a product that has N-palmitoyl-ethanolamine in its composition. This substance regulates mast cell activation and microglia activation. It is considered by many to be very effective in reducing neuropathic pain. Phosphatidylserine is an organic compound found naturally in the cell membranes of living organisms. It plays an important role especially in cells of the central nervous system. It positively influences neuronal cell membrane functions such as neurotransmitter release, signal transduction, and intercellular communication. Phosphatidylserine is therefore an essential substance for basic brain functions, activates and regenerates nerve cells. It increases the secretion of neurotransmitters such as dopamine, acetylcholine and noradrenaline and increases the concentration of glucose in the brain. This has a beneficial effect on central nervous system functions such as perception, memory and association. It may also have a beneficial effect on stress management. Pine pollen due to the presence of a large number of amino acids, vitamins and minerals has a nourishing function for the body. Pine pollen contains naturally occurring androgens i.e. testosterone and DHEA. DHEA is produced in the adrenal glands and adrenal exhaustion. Daily stress or an unhealthy diet can affect its production. Low DHEA levels are often manifested by fatigue, reduced immunity, reduced sex drive, depression or cognitive decline, among other symptoms. Red root (Lat. Ceanothus americanus) has astimulating and tonic effect on the lymphatic system. It shows astringent and tonic properties to mucous membranes. It improves the production of T lymphocytes. It has an anti-inflammatory effect on the liver and spleen. Red root is a strong blood coagulant. This herb should not be combined with pharmacological coagulants and anticoagulants. REM Repair is a product by Nutrined which contains GABA, Melissa officinalis, Valerian and vitamin B6. The ingredients in this product have a calming and sleeping effect. Resveratol is an organic polyphenolic compound of plant origin. In the context of Lyme disease, resveratrol from Japanese Knotweed is relevant. Japanese Knotweed standardised to a specific amount of resveratrol can be used in therapy. In this case please refer to the properties described for Japanese Knotweed. Rg3 Nasal Spray Nutrined. The active ingredients in this product will support microglia activation in nervous system inflammation, adrenal fatigue and neurodegenerative changes. Rhodiola (Lat. Rhodiola rosae) is another excellent adaptogen that enhances the body's response to physical, mental and emotional stress. It is often used as a support for adrenal fatigue syndrome. It is recommended for feelings of chronic fatigue as well as problems with concentration. It also shows antidepressive effects. It has a protective effect on mitochondria. Some people experience a feeling of internal shakiness after taking Rhodiola. Do not take it at night until you know if it causes similar problems for you. Salvia (Red sage, Lat. Salvia miltiorrhiza) is a herb that, like Chinese skullcap is used as a modulator of the cytokine cascade, i.e. it regulates the complex inflammatory process triggered during infections, including those taking place in the nervous system. In addition, it protects the integrity of the lymphatic endothelium, limiting cell invasion by pathogens or the harmful effects of cytokines. We have written about the importance of modulating the cytokine cascade in the “Practical Guide- Application of Herbal Therapies for Lyme Disease and Coinfections”. An important property of Salvia is the protective function of the Golgi apparatus of nerve cells. The Golgi apparatus is an organelle found in the cell that serves to chemically modify the substances produced by the cell, sort them and distribute them within the cell. The Golgi apparatus of nerve cells is damaged in the course of Lyme and tick-borne diseases. It is also damaged in neurological diseases such as multiple sclerosis, Parkinson's disease or Alzheimer's disease. If the Golgi apparatus is damaged in the course of a tick-borne disease, symptoms similar to those of the above-mentioned neurological diseases can develop. Please note the great importance of Salvia in the context of tick-borne diseases. This herb should already be added as one of the primary herbs in the treatment of Lyme disease. If you have used the Buhner Protocol as a basic core therapy and you have increased neurological problems then you can increase the dose of Salvia by up to 2-3 times. This herb is safe to use. If you have been using herbs other than Buhner's herbs as the core of therapy, and you have increased neurological symptoms, then think about introducing this herb as an adjunct to therapy. SAMe (S-adenosyl L-methionine) is a naturally occurring substance and is a source of methyl groups in the metabolism of every cell. It boosts mood, improves methylation and reduces joint pain. One alternative mechanism for depression can be disorders of one-carbon metabolism, the so-called one-carbon cycle, associated with the transmethylation reaction. A form of regulation of disorders of one-carbon metabolism is the direct administration of SAMe. The efficacy of SAMe in the treatment of depression is the subject of many scientific studies. It is likely that SAMe may have a neuroprotective effect in the central nervous system as well as in mild cognitive impairment and may prevent cognitive decline. Sarsaparilla (Lat. Smilax glabra) reduces the strength of the Herx response through its ability to bind endotoxins in the blood that are released by dead spirochetes and other co-infections. Due to its ability to bind endotoxin in the blood, it contributes to blood purification. It exhibits anti-inflammatory effects in joint symptoms. It manifests broad systemic effects, including its ability to cross the blood-brain barrier, it shows effects on the brain, it helps to reduce cognitive impairment and protects it from neurodegeneration. Sarsaparilla restores autoimmune responses. It helps to alleviate skin symptoms associated with Lyme disease. It has a protective effect on the liver. This herb enhances the effects of other herbs and medications used for Lyme disease. Schisandra (Lat. Schisandra chinensis) reduces stress hormone levels in the body. Schisandra's adaptogenic properties help to maintain internal balance and reduce the levels of biochemical stress indicators in the body. The plant effectively controls adrenaline and serotonin fluctuations caused by stress. It therefore combats stress-related adrenal fatigue. Schisandra includes lignans which have a protective effect on the liver, preventing its damage and accelerating regeneration. It has a positive effect on the heart. Schisandra is safe and well tolerated and has no side effects. However, it should not be consumed by people with nervous hyperactivity, insomnia, high blood pressure and heart disorders. Sealantro Metal Detox by Nutramedix is a unique blend of extracts from three plants: chlorella, Chondracanthus chamissoi seaweed and coriander leaves. It helps to detoxify the body from heavy metals, various biotoxins and many other toxic substances. Siberian ginseng (Eleuthero, Lat. Eleutherococcus senticosus) is mainly considered to be a herb which boosts energy and vitality. It counteracts the feeling of tiredness. It is also a very good adaptogen. Adaptogens are a unique group of natural ingredients that help the body adapt to environmental stress. Siberian ginseng has a positive effect on the functioning of the immune system, but also on the axis of the hypothalamus, pituitary, adrenal glands. It has a stress-relieving effect by increasing the level of leukocytes and nucleic acids. Ginseng stimulates secretion of serotonin, the so called happiness hormone, influencing good mood and soothing mood swings. The use of this herb also increases the level of dopamine, a hormone whose deficiency can cause problems with getting up in the morning, decreased concentration and a feeling of tiredness. It has also been shown to enhance psychophysical performance and to have an anti-anxiety effect. People with hypertension should be careful with Siberian ginseng. Sida acuta is classified as a systemic herb. Sida acuta has a very broad spectrum of antimicrobial activity and, by the way, will also work on Babesia and Bartonella. It helps not only with tremors, but also with the rather common symptom of "buzzing" or "electricity flowing through the body". This herb also reduces Lyme neurotoxins (e.g. quinolinic acid). It also shows a protective effect against erythrocytes (red blood cells) which is particularly important in Babesia and Bartonella infections. Sparga Sulphur Detox by Nutramedix is an extract of asparagus root. It helps to remove sulfoantibiotics and other sulfonamide-based drugs from the body, which block the body's sulphur pathways and toxin conjugation pathways. Stephania is a herb that already occupied an important place in the treatment of Lyme disease in the first edition of Buhner's book. Initially, Buhner used Stephania as the primary herb for neurological symptoms. This herb has now been replaced by Gou teng (Uncaria rhynchophylla). Stephania is still a great herb, but is recommended by Buhner mainly for ocular Lyme disease and Bell's palsy. Stephania has a protective effect on neurological structures in the brain. It exhibits anti-inflammatory effects both in the nervous system and in inflammatory conditions of the joints, especially those of autoimmune origin, such as rheumatoid arthritis. The active ingredients of this herb, also have a positive effect on the cardiovascular system. Stephania is a strong calcium channel blocker. Approximately half of people who use pharmaceutical calcium channel blockers have a problem when combining them with Stephania root. When taking such drugs, the introduction of Stephania into therapy should be consulted with your doctor. It is not recommended for people with atrioventricular (AV) block. The herb should not be combined with antiarrhythmic drugs and with digoxin. Taurine is the second most common amino acid in muscles after glutamine. One of its best known properties is that it helps with muscle regeneration after training. However, taurine has many more important functions for the body. This amino acid is important for the proper function of the heart and cardiovascular system. One of taurine's most important functions is the regulation of excitable brain tissues, which are responsible for, amongst other things, seizures - a characteristic symptom of epilepsy. This is most likely because taurine indirectly influences the level and regularity of GABA, an important neurotransmitter. Taurine has a positive effect on liver function, increasing the protection of this organ against the effects of toxins, oxidative stress or other harmful factors. Taurine can also reverse the effects of biochemical processes that impair hearing or completely eliminate tinnitus. This is because taurine restores the correct flow of calcium ions in auditory cells, resulting in improved hearing. Taurine should not be combined with psychotropic drugs. Taurine should not be taken by people suffering from bipolar disorder. Teasel root (Lat. Dipsacus sylvestris) has a bacteriostatic effect against Lyme spirochetes, i.e. it inhibits their development and multiplication. Teasel root has analgesic, anti-inflammatory and anti-rheumatic effects. Compounds contained in the root and leaves of the plant support regeneration of connective tissue and minimize bone mass loss. They have a strengthening effect on bones and tendons and are helpful in long-term swelling and joint pain. Tryptophan is an essential amino acid for the proper functioning of the nervous system. Its deficiency results in decreased energy and worse mood. Tryptophan takes part in the synthesis of serotonin, the so-called happiness hormone, and in the production of melatonin, the sleep hormone. If we do not take in the right amount of this amino acid, we experience serotonin deficiency, which results in mood drops, anxiety, insomnia, aggressiveness or depressive disorders. It also plays an important role in the synthesis of rhodopsin, the light-sensitive pigment that makes us see after dark. In addition, it is responsible for regulation of noradrenaline and dopamines, reduction of hyperactivity and tension, regulation of metabolism and strengthening of immunity. Turmeric/Curcumin - Turmeric is a well-known spice with an intense yellow-orange colour and curcumin is the active ingredient isolated from turmeric. Curcumin exhibits powerful antioxidant properties as well as antibacterial, antiviral and anti-inflammatory properties. Curcumin brings relief from joint pain and contributes to joint regeneration. It is believed to have a therapeutic effect in the scope of osteoarthritic changes due to its antioxidant and anticatabolic properties and by reducing the synthesis of inflammatory mediators. Zeolite is a natural mineral of volcanic origin. Its main ingredient is clinoptilolite. Zeolite releases valuable components into the body while binding many harmful substances such as lead, cadmium, arsenic, chromium, nickel and ammonium ions. It is important to use high purity Zeolite designed for internal use. We recommend that you purchase a certified product. You can find high quality zeolite at https://www.zeolite-bentonite.com/ 5-HTP (5-hydroxytryptophan) helps to create serotonin. Serotonin is the happiness hormone. 5-HTP balances out mood swings and helps with depression. The actual antidepressant effect is particularly relevant for people who have been affected by tryptophan deficiency for various reasons, whether due to poor diet or upregulation of tryptophan-metabolising enzymes resulting from chronic inflammation. Combining 5-HTP with green tea extract is strongly recommended. Remember, do not use both Tryptophan and 5-HTP at the same time. Both products affect the regulation of tryptophan levels in the body. In the same way, if you are using Tryptophan and you do not see effects then there is no point in including 5-HTP or vice versa. All herbs and supplements can be purchased on Lymeherbs Store at www.lymeherbs.eu SUGGESTED SELECTION OF HERBS Note: before introducing herbs read the descriptions above. We would like to to point out that you should try to compare herbs in terms of symptoms. Many of them overlap. If you plan your herbal selection well, you will reduce the amount of products you need and perhaps a particular herb will help you with several symptoms at once. For example: you have ocular symptoms associated with Lyme disease, neurological symptoms and cardiac symptoms. One herb for both ocular, neurological and cardiac symptoms is Stephania. Introduce this herb and observe at what level it benefits you. Make a note of any observations in the Therapy Planner. It is important to take into account your symptoms, herbs you started to take and observe what are the improvements in a few weeks. This is an important part of the therapy because everyone reacts differently and each individual can be helped by different herbs. You are treating not so much the disease but yourself as an individual. Your observations are invaluable. NEUROBORRELIOSIS -- BASIC HERBS FOR NEUROLOGICAL SYMPTOMS As recommended by Buhner, introduce the Gou teng (Lat. Uncaria rhynchophylla) and Tryptophan as a basis. We suggest to extend supplementation with: NAC (N-acety- L-cysteine), Omega acids, vitamin B complex, vitamin D3 and coenzyme Q10. Glutathione as a powerful antioxidant would also be useful. Additional supplementation is important to optimise proper nervous system function. In a large group of people Gou teng and Tryptophan contributes to the reduction of a large group of neurological symptoms. Observe your body's reaction to what extent you see improvement. If it is enough then maintain this regimen. Remember that neurological changes will not go back in 1-2 months. In the case of neuroborreliosis it is good to maintain taking Gou teng and tryptophan for the entire period of therapy. If they do not serve you, then withdraw them. If you see an improvement but are still struggling with some troublesome symptoms then maintain Gou teng and Tryptophan in the therapy and add another herb for a specific symptom. Rg3 Nasal Spray Nutrined is also an interesting product especially for inflammation of the nervous system and neurodegenerative changes. Ashwagandha (Indian ginseng, Lat. Withania somnifera) is a herb which has a very positive effect on the nervous system and is worth supporting in case of neurological problems. Its effect in Lyme disease is multidirectional, as you can learn from the previous descriptions. For this reason, it blends in very well with the therapy. DEMYELINATION OF NEURONS In the course of neuroborreliosis very often demyelinating changes occur. While dealing with this problem it is necessary to introduce into therapy something that will stimulate the nerve growth factor (NGF) essential for neuronal proliferation and survival and something that will stimulate the process of myelinisation (production of myelin sheaths - responsible for protection and nutrition - around axons of nerve cells). If you are experiencing demyelinating changes then you could try including: Lion's mane, Chinsese senega or BDNF Essentials®. What to choose? Chinsese senega and Lion's mane have similar effects, i.e. they will stimulate the nerve growth factor (NGF) essential for neuronal proliferation and survival and will stimulate the process of myelination. Buhner, in one of his articles, suggests that a tincture of Chinese senega is better for an aggravated condition and Lion's mane for a milder condition. Alternatively, you can start with a tincture of Chinese senega and after time switch to Lion's mane. If you don't see improvement on these herbs then try including BDNF Essentials® by Researched Nutritionals®, which stimulates brain-derived neurotrophic factor (BDNF), a protein secreted by neurons that belongs to the nerve growth factor family. BELL'S PALSY For Bell's palsy, the Stephania recommended by Buhner works best. You can enhance its effect by adding Kudzu. Vitamin B12 supplementation is also advisable. NEUROGENIC PAIN If you are struggling with this type of pain, try to administer Greater celandine (be sure to read its description and contraindications before incorporating this herb into your therapy) and Kudzu. Kudzu is also useful for the symptom of a feeling of "pressure" in the head. If this does not help then try the PEA preparation by Nutrined. CBD oil due to its analgesic properties can also give good results. When deciding on CBD oil pay attention to its concentration. For autoimmune disorders, nervous system diseases, chronic pain, increased inflammation or severe migraines, a higher concentration of CBD oil is recommended. A low concentration of the oil cannot have an effect. However, there are some people who need to start with small doses and low concentrations and gradually increase the intensity. Also noteworthy is Buhner's recommended combination of Angelica sinensis tincture with Salvia miltiorrhiza tincture. TREMORS Sida acuta works very well in tremors. Mucuna pruriens recommended by Buhner as a precursor to L-dopa can also be helpful. SAMe is also effective in this ailment. Magnesium supplementation will also be recommended. REMOVAL OF BACTERIAL NEUROTOXINS If you want to support the detoxification of the central nervous system from neurotoxins you can try to take: Burbur-Pinella, Sida acuta tincture or Angelica sinensis tincture (remember not all at once) it is also worth including Glutathione and NAC inaddition. Which is best to start with? If you are concurrently treating Bartonella or Babesia or have symptoms of tremors or current flow through the body then choose Sida acuta. Sida acuta is part of the Buhner protocol for Bartonella and Babesia. Burbur-Pinella is certainly worthy of attention. In our opinion, it is a very effective preparation used in the detoxification of the nervous system and is worth having in your therapy. Whichever product you choose it is the addition of glutathione and NAC that will bring good results. DEPRESSION Depression often accompanies people with Lyme disease. It can have various causes. Below you have listed some natural products that can act as a support. The cause of depression varies. Please consider the following suggestions as adjunctive. They can work for you but if your depression is very deep, you should seek help from a specialist. Psychological help can be very useful in coping with the illness. Many people also find meditation helpful. Calming down and regaining inner balance are advisable. Tryptophan and 5-HTP are involved in the synthesis of serotonin, the so-called happiness hormone. Stimulating the synthesis of serotonin has a good effect in some people. Remember, do not use both Tryptophan and 5-HTP at the same time. Both products affect the regulation of tryptophan levels in the body. In the same way, if you are using Tryptophan and you do not see effects, there is no point in including 5-HTP or vice versa. There are also recent reports of the effects of methylation disorders on mental health. In this case you could try introducing SAMe (S-adenosyl L-methionine) plus vitamin B complex, vitamin D3 with K2, vitamin A, vitamin C, magnesium, zinc, selenium, potassium, omega 3 acids. Supportive therapy can still be included: Siberian ginseng if you experience the feeling of fatigue. Motherwort (Lat. Leonurus cardiaca) for accompanying migraine pains and when you need to calm down. Melatonin when you have trouble sleeping. CHRONIC FATIGUE Chronic fatigue is a symptom that accompanies most people with Lyme disease. In many people, a tincture of Siberian Ginseng at a concentration of 2:1 produces good results. Sometimes Ginseng is insufficient. In this case, one can wonder whether the cause of chronic fatigue is not mitochondrial dysfunction or adrenal exhaustion. It is impossible to determine conclusively whether in your case the problem is mitochondrial or adrenal, or perhaps both. Try one of the following and observe your body to see if it is a sufficient solution for you. MITOCHONDRIAL DYSFUNCTION/DEPLETION Mitochondria, the so-called power plants of cells, produce the energy necessary for the proper functioning of the whole body, i.e. each of the organs and tissues. Lyme disease causes weakening of mitochondria, they are not able to work properly, they cannot keep up with producing enough energy in damaged cells. By rebuilding the mitochondria, we guarantee that the body is supplied with enough energy to regenerate the tissues, which results in the improvement of the functioning of the whole body and the removal of the feeling of fatigue. Products by Researched Nutritionals® are very effective formulations. Researched Nutritionals® carries out advanced research on products and focuses largely on mitochondrial restoration. Very good products in this area are: ATP Fuel ATP 3600 NT Factor EnergyTM For truly optimised performance, Researched Nutritionals® recommends combining three products at once. You can also use them individually. From our experience, the use of ATP Fuel or ATP 3600 gives very good results and in our opinion these are some of the most effective products for the feeling of chronic fatigue. The descriptions of these products can be found in the list of herbs in alphabetical order. Another option for supporting mitochondrial function is Buhner's recommendations. In this case, it is the best to combine all the recommended elements, i.e.: D-ribose (it acts as a fuel for energy production but it should not be administered to people with metabolic syndrome and diabetes who have elevated levels of glycation) NADH (is a part of the electron transport chain that produces energy) L-arginine (it supports mitochondrial function through effects on the nitric oxide pathway) L-carnitine (transports fats to the mitochondria) Coenzyme Q10 (key compound in the Krebs cycle) Alpha lipoic acid (it activates an enzyme called 5'AMP-activated kinase) Motherwort (Lat. Leonurus cardiaca) Dr. Horowitz also places great emphasis on supporting mitochondrial function. In his opinion, the following products (all of them) should be used for this purpose: L-arginine (it supports mitochondrial function through effects on the nitric oxide pathway) Alpha lipoic acid (in activates an enzyme called 5'AMP-activated kinase) Resveratrol (it can increase mitochondrial production) NT Factor EnergyTM /ATP Fuel (it is described in the herbarium above) L-carnitine (it transports fats to the mitochondria) Coenzyme Q10 (key compound in the Krebs cycle) NADH (is a part of the electron transport chain that produces energy) D-ribose (it acts as a fuel for energy production but it should not be administered to people with metabolic syndrome and diabetes who have elevated levels of glycation) For mitochondrial protection William Rawls recommends: Glutathione NAC Alpha lipoic acid Vitamin C Coenzyme Q10 Vitamin D ADRENAL EXHAUSTION/FATIGUE Another cause of chronic fatigue can also be called adrenal exhaustion. Adrenal fatigue or adrenal exhaustion is a medical condition in which the adrenal glands are unable to produce adequate amounts of hormones necessary for the body to function properly. This imbalance means that the person experiences normal daily stresses as overwhelming, causing total exhaustion and fatigue that seems endless, no matter how much sleep, rest or relaxation was provided. The most effective in this case seems to be: Adrenal Cortex which contains bovine adrenal cortex. Or Energy Multi-Plex which supports adrenal function but is based on a vegan formula rather than glandular. Again, the inclusion of D-ribose and a higher dose of coenzyme Q10 gives good results. BRAIN FOG, CONCENTRATION AND MEMORY PROBLEMS Herbs to start with are Gotu kola or Ginkgo biloba. Combine this with additional supplementation with coenzyme Q10, magnesium, omega 3 acids, taurine and vitamin B complex. Note that in the Therapy Planner there are other herbs listed for brain fog problems, yet these are herbs that are helpful for other symptoms e.g. ATP Fuel is recommended for brain fog and chronic fatigue. Lion's mane is recommended for brain fog and neurological symptoms. Rhodiola rosae is a very good adaptogen recommended for brain fog, chronic fatigue (but not as an individual herb) and excessive stress. JOINT PROBLEMS To start, we recommend teasel root tincture, collagen, selenium, glucosamine with chondroitin, MSM and curcumin (or turmeric). If you find the Teasel root tincture insufficient then you can replace it with Boswellia serrata or Devil's claw. Along with these also use collagen, selenium, glucosamine with chondroitin, MSM and curcumin (or turmeric) inparallel. TREMOR, MUSCLE NUMBNESS Above all, include supplementation with magnesium, vitamins B6 and B12 and folic acid. You can also introduce herbs. If you have an additional "electric shock" sensation, then Sida acuta will work well. It can be helpful if the problem of trembling or numbness comes from the nervous system. Ginkgo biloba will help if the underlying cause of your problems is more of a peripheral circulation disorder. If you have cold extremities at the same time you can start with this herb. CARDIOVASCULAR PROBLEMS For heart problems, Hawthorn is the primary herb. Remember, however, that people with low blood pressure should avoid it. Stephania also deserves attention and if, along with your cardiovascular problems, you also have neurological problems and/or eye problems then try to take this herb. Observe your body's reaction and exactly what improved while using Stephania. UseMotherwort if your heart problems are of a nervous nature. This herb has a calming effect. Japanese knotweed is a source of resveratrol. It has a wonderful effect on the cardiovascular system. This herb is the basic herb in the Buhner Protocol, so the Buhner Basic Protocol itself has a protective effect on the cardiovascular system. And don't forget the necessary supplementation. Omega acids are essential for heart health. Magnesium regulates neuromuscular excitability by reducing signal conduction which prevents uneven and accelerated heart rate. Vitamin C, D, E and the B vitamin group are also essential supplementation for people with cardiovascular problems. As a result of myocardial ischemia, the level of L-carnitine in the body decreases. Supplementation through diet or supplementation is advisable. Taurine, on theother hand, is the most abundant amino acid in the heart. It is essential for the proper functioning of heart muscles. SLEEP PROBLEMS Insomnia, problems with falling asleep, waking up during the night, shallow sleep is a problem of many people suffering with Lyme disease. The cause of this problem can be very different. You can use the following solutions. It is good to combine this with relaxation techniques or meditation, preferably before bedtime, to calm the body. If none of the following methods help and you still want to stick to natural ways of fighting insomnia then try acupuncture. Several directions can be taken when dealing with sleep problems: Taking melatonin before bedtime. Melatonin is a neurohormone that regulates sleep and wakefulness throughout the day. Melatonin supplementation will help if your insomnia problems are caused by your body's dysregulation of melatonin production. If you have problems with falling asleep, we recommend the melatonin nasal spray - Chronobiane Immediat spray by PiLeJe. This product combines melatonine and hawthorn extract. If you have a problem with waking up at night then we recommend the product - Chronobiane LP 1.9 mg by PiLeJe. This product combines melatonin with Bambusa arundinacea (extract) bamboo powder and Adansonia digitata baobab powder. REM Repair containing GABA, Melissa officinalis, valerian, vitamin B6. In this way, you supply GABA to your body (an amino acid produced in the brain, a substance described as a natural sedative for the body) and herbs that have a calming and sleeping effect. Amantilla Nutramedix is an extract made from the root of Valeriana officinalis, commonly known as Valerian. By using it, you will achieve a calming and sleeping effect. Ashwagandha is a good adaptogen that also helps with insomnia by calming the body. It can be helpful for mild sleep problems LOSS OF LIBIDO We suggest starting with a combination of Maca root and Pine pollen. It is also worth supplementing with L-arginine, L-choline, L-phenylalanine, L-tyrosine and zinc. OEDEMA, SWELLING AND SLUGGISH LYMPHATIC SYSTEM The most effective herbs for this ailment are Cleavers and Red root. Try out which one works better for you. In addition, drinking nettle infusion will act as a diuretic and speed up the removal of water from the body. References: Darin Ingels “The Lyme Solution. A 5-Part Plan to Fight the Inflammatory Auto-Immune Response and Beat Lyme Disease.” Gerard Nowak „Surowce roślinne stosowane w wyczerpaniu psychofizycznym i stresie” Jacob Teitelbaum “From Fatigued to Fantastic!” Marek Krzystanek, Artur Pałasz, Ewa Krzystanek, Irena Krupka-Matuszczyk, Ryszard Wiaderkiewicz, Rafał Skowronek „S-adenozylo L-metionina w schorzeniach OUN.” Pawel Malinowski " Umysł, ciało, duchowość." Piotr Migas, Magdalena Heyka „Glistnik jaskółcze ziele (Chelidonium majus L.) we współczesnej terapii - wskazania i bezpieczeństwo stosowania”. Katedra i Zakład Farmakognozji z Ogrodem Roślin Leczniczych, Wydział Farmaceutyczny, Gdański Uniwersytet Medyczny Kierownik Katedry i Zakładu: dr hab. Mirosława Krauze-Baranowska, prof. nadzw. Richard I. Horowitz “How Can I Get Better?” An Action Plan for Treating Resistant Lyme & Chronic Disease” Stephen Harrod Buhner: “Herbal Antibiotics: Natural Alternatives for Treating Drug-Resistant Bacteria.” Stephen Harrod Buhner: “Healing Lyme Disease Coinfections: Complementary and Holistic Treatments for Bartonella and Mycoplasma.” Stephen Harrod Buhner: “Healing Lyme: Natural Healing of Lyme Borreliosis and the Coinfections Chlamydia and Spotted Fever Rickettsiosis.” Stephen Harrod Buhner “Natural Treatments for Lyme Coinfections: Anaplasma, Babesia, and Ehrlichia.” Stephen Harrod BuhnerHerbal Antivirals: Natural Remedies for Emerging Resistant and Epidemic Viral Infections.” William Rawles “Unlocking Lyme. Myths, truths and practical solutions for chronic Lyme disease.”
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